EPIDEMIOLOGY OF ROCKY MOUNTAIN SPOTTED FEVER IN BRAZIL, 2010-2020

Autores

  • Fernanda Cristina Poscai Ribeiro
  • Kleber Fernando Pereira
  • Dayane Kelly Sabec-Pereira
  • Alexandre Daronco
  • Alcântara Ramos de Assis César

DOI:

https://doi.org/10.25110/arqsaude.v27i3.2023-028

Palavras-chave:

Rocky Mountain Spotted Fever, Severe Headache, Epidemiology

Resumo

Rocky Mountain spotted fever is a tick-borne rickettsiosis. The main clinical signs and symptoms are fever, severe headache, rashes and myalgia. It is considered difficult to diagnose and underreported. The study aims to descriptively analyze the epidemiology of cases of Rocky Mountain spotted fever in Brazil from 2010 to 2021. This is a retrospective cohort study that statisticall analyzes the cases of spotted fever in Brazil between 2010 and 2020 through data obtained by the Information System of Notifiable Diseases. The proportions of spotted fever cases were calculated according to: sex, age, race/color, infection environment and evolution. There are 1967 cases were confirmed. The regions with the most cases were the Southeast (n%=72.24) and the South (n%=24). However, there are 4 deaths in the south while the lethality coefficient from the southeast is 47.78%. The most affected age group was 40-59 years old (n%=34.87), and 20-39 years old (n%=28.98). 71.17% of the cases are male. As for color/race, 60% of the cases are in whites. As for the infection environment, 35.23% are at home, 15.3% are at work, 26.13% are leisure places. The prevalence in males and the predominant age group 20-59 years can be linked to work activity, which leaves hem more exposed to ticks. The high numbers in adulthood can also be related to ecotourism. The lethality of the disease differs between the South and Southeast regions. One explanation for this phenomenon would be the different etiological agents, R. rickettsi, predominant in the Southeast, generating more severe clinical conditions.

Referências

ARAÚJO RP, NAVARRO MB, CARDOSO TA. Febre maculosa no Brasil: estudo da mortalidade para a vigilância epidemiológica. Cadernos Saúde Coletiva 2016;24(3):339-346. Doi:10.1590/1414-462x201600030094

BLANTON, L. S. et al. The Rickettsioses. Infectious Disease Clinics Of North America, v. 33, n. 1, p. 213-229, 2019. Elsevier BV. http://dx.doi.org/10.1016/j.idc.2018.10.010.

CAMPOS, S. D. E.; CUNHA, N. C.; ALMOSNY, N. R. P. Brazilian Spotted Fever with an Approach in Veterinary Medicine and One Health Perspective. Veterinary Medicine International, v. 2016, p. 1-7, 2016. Hindawi Limited. http://dx.doi.org/10.1155/2016/2430945.

CHEN, L. F. et al. What's New in Rocky Mountain Spotted Fever? Infectious Disease Clinics Of North America, v. 22, n. 3, p. 415-432, 2008. Elsevier BV. http://dx.doi.org/10.1016/j.idc.2008.03.00

COSTA GA, CARVALHO AL, TEIXEIRA DC. Spotted fever: update. Revista Médica de Minas Gerais. 2016;26 (Supl 6):S61-S64. Doi: 10.5935/2238-3182.20160059

COUTO DV, MEDEIROS MZ, HANS FILHO G, LIMA AM, BARBOSA AB, VICARI CF. Brazilian spotted fever: the importance of dermatological signs for early diagnosis. Anal Brasileiro de Dermatologia 2015;90(2):248-50. doi: 10.1590/abd1806-4841.20153087

DANTAS-TORRES, F. Rocky Mountain spotted fever. The Lancet Infectious Diseases, v. 7, n. 11, p. 724-732, 2007. Elsevier BV. http://dx.doi.org/10.1016/s1473-3099(07)70261-x.

DEL FIORI, F.S et al. A febre maculosa no Brasil. Pan American Journal of Public Health. n.6, p.461-467, 2010.

DÍAZ JS, CATAÑO JC. Fiebre manchada de las montañas rocosas: ni tan manchada ni tan montañosa como pensábamos. Infectio 2010;14(4):264-276. Doi:10.1016/s0123-9392(10)70120-x

FACCINI-MARTÍNEZ ÁA, OLIVEIRA SV, CERUTTI JUNIOR C, LABRUNA MB. Febre Maculosa por Rickettsia parkeri no Brasil: condutas de vigilância epidemiológica, diagnóstico e tratamento. Journal of Health & Biological Sciences 2018;6(3):299. Doi:10.12662/2317-3076jhbs.v6i3.1940.p299-312.2018

FERREIRA LF, SANTOS NP, SILVEIRA AL, PENA IC, REIS JR, AMÂNCIO ND. Perfil Epidemiológico da Febre Maculosa no Brasil. Revista Médica de Minas Gerais 2021;31. Doi:10.5935/2238-3182.20210030

IBGE. Conheça o Brasil – População COR OU RAÇA. https://educa.ibge.gov.br/jovens/conheca-o-brasil/populacao/18319-cor-ou-raca.html

LABRUNA MB, KASAI N, FERREIRA F, FACCINI JL, GENNARI SM. Seasonal dynamics of ticks (Acari: Ixodidae) on horses in the state of São Paulo, Brazil. Veterinary Parasitology 2002;105(1):65-77. Doi: 10.1016/s0304-4017(01)00649-5.

LEMOS ER, ROZENTAL T, VILLELA CL. Brazilian spotted fever: description of a fatal clinical case in the State of Rio de Janeiro. Revista da Sociedade Brasileira de Medicina Tropical 2002;35(5):523-525. Doi:10.1590/s0037-86822002000500017

LUZ, H. R. et al. Epidemiology of capybara-associated Brazilian spotted fever. Plos Neglected Tropical Diseases, v. 13, n. 9, p. 7734-7740, 2019. Public Library of Science (PLoS). http://dx.doi.org/10.1371/journal.pntd.0007734

OLIVEIRA SV, GUIMARÃES JN, RECKZIEGEL GC et al. An update on the epidemiological situation of spotted fever in Brazil. Journal of Venomous Animals and Toxins including Tropical Diseases 2016;22(1). Doi:10.1186/s40409-016-0077-4

OLIVEIRA, S. V. et al. Predictive Factors for Fatal Tick-Borne Spotted Fever in Brazil. Zoonoses And Public Health, v. 64, n. 7, p. 44-50, 2017. Wiley. http://dx.doi.org/10.1111/zph.12345.

OTOMURA, F. H. et al. Probability of occurrence of the Brazilian spotted fever in northeast of Paraná state, Brazil. Revista Brasileira de Parasitologia Veterinária, v. 25, n. 4, p. 394-400, 2016. FapUNIFESP (SciELO). http://dx.doi.org/10.1590/s1984-29612016060.

RYDKINA, E. et al. Infection of Human Endothelial Cells with Spotted Fever Group Rickettsiae Stimulates Cyclooxygenase 2 Expression and Release of Vasoactive Prostaglandins. Infection And Immunity, v. 74, n. 9, p. 5067-5074, 2006. American Society for Microbiology. http://dx.doi.org/10.1128/iai.00182-06.

SECRETARIA DE VIGILÂNCIA EM SAÚDE DOENÇAS INFECCIOSAS E PARASITÁRIAS. Doenças Infecciosas e Parasitárias: guia de bolso. 8. ed. Brasília, 2010

WALKER, D. H. Rocky Mountain spotted fever: a disease in need of microbiological concern. Clinical Microbiology Reviews, v. 2, n. 3, p. 227-240, 1989. American Society for Microbiology. http://dx.doi.org/10.1128/cmr.2.3.227.

WALKER, D. H.; VALBUENA, G. A.; OLANO, J.P. Pathogenic Mechanisms of Diseases Caused by Rickettsia. Annals Of The New York Academy Of Sciences, v. 990, n. 1, p. 1-11, 2003. Wiley. http://dx.doi.org/10.1111/j.1749-6632.2003.tb07331.

Downloads

Publicado

14-04-2023

Como Citar

Ribeiro, F. C. P., Pereira, K. F., Sabec-Pereira, D. K., Daronco, A., & César, A. R. de A. (2023). EPIDEMIOLOGY OF ROCKY MOUNTAIN SPOTTED FEVER IN BRAZIL, 2010-2020. Arquivos De Ciências Da Saúde Da UNIPAR, 27(3), 1512–1527. https://doi.org/10.25110/arqsaude.v27i3.2023-028

Edição

Seção

Artigos