BUMETANIDE IN AUTISM SPECTRUM DISORDER

Autores

  • Lucas da Silva Moreira
  • Gislei Frota Aragão

DOI:

https://doi.org/10.25110/arqsaude.v26i3.2022.8774

Resumo

Objectives: This study aimed to make a bibliographic update on the already published data on bumetanide, addressing the main information on its use in Autism Spectrum Disorder (ASD).  Methods: This was an integrative narrative review in which the following databases were used: Web of Science, MEDLINE, ScienceDirect, and Scielo. The descriptors used were: Autism Spectrum Disorder, Autistic Disorder and Bumetanide. It was considered only articles published in English and French. Original articles, randomized clinical trials, case reports, and review articles were included. Results: The results show that the use of bumetanide alters regions of the brain linked to the positive development of language, improvement of visual contact, improvement in social interactions, among others. Studies are also concerned about the safety and efficacy of bumetanide in ASD since several adverse effects have been reported. The most frequent were hypokalemia, polyuria, and loss of appetite. Conclusion: Bumetanide has proven as effective in improving some important symptoms in ASD, especially linked to language and social interaction, however, studies with larger groups of patients and with longer treatment and observation time are needed to confirm the efficacy and clarify the safety profile in use for people with ASD.

Downloads

Publicado

29-09-2022

Como Citar

Moreira, L. da S., & Aragão, G. F. (2022). BUMETANIDE IN AUTISM SPECTRUM DISORDER. Arquivos De Ciências Da Saúde Da UNIPAR, 26(3). https://doi.org/10.25110/arqsaude.v26i3.2022.8774

Edição

v. 26 n. 3 (2022)

Seção

Artigos

Licença

 

Os Direitos Autorais para artigos publicados são de direito da revista. Em virtude da aparecerem nesta revista de acesso público, os artigos são de uso gratuito, com Creative Commons Attribution 4.0 International License.

A revista se reserva o direito de efetuar, nos originais, alterações de ordem normativa, ortográfica e gramatical, com vistas a manter o padrão culto da língua e a credibilidade do veículo. Respeitará, no entanto, o estilo de escrever dos autores.

Alterações, correções ou sugestões de ordem conceitual serão encaminhadas aos autores, quando necessário. Nesses casos, os artigos, depois de adequados, deverão ser submetidos a nova apreciação.

As opiniões emitidas pelos autores dos artigos são de sua exclusiva responsabilidade.